To prevent cisplatin nephropathy
WebApr 15, 2012 · The protective effects of BCP against biochemical and histological markers of nephropathy were absent in CB(2) knockout mice. Thus, BCP may be an excellent therapeutic agent to prevent cisplatin-induced nephrotoxicity through a CB(2) receptor-dependent pathway. Given the excellent safety profile of BCP in humans it has … WebFeb 16, 2024 · Cisplatin can harm an unborn baby if the mother or the father is using cisplatin. If you are a woman, do not use cisplatin if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 14 months after your ...
To prevent cisplatin nephropathy
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WebAmong drugs with a potential for renal toxicity, platinum salts, and especially cisplatin is a … WebApr 15, 2024 · Chronic kidney disease (CKD) is a serious public health problem characterized by progressive kidney function loss leading to end-stage renal disease (ESRD) that demands dialysis or kidney ...
WebApr 14, 2024 · Africa, particularly sub-Sharan Africa (SSA), faces major challenges in respect to chronic kidney disease (CKD). There is a rising prevalence due to the combined effects of hypertension, diabetes, and human immunodeficiency virus (HIV) (and the interaction between them) and the effect of apolipoprotein L1 (APOL1) variants on the susceptibility … WebNumerous compounds have been studied to prevent cisplatin nephrotoxicity but only …
WebRisk of drug nephrotoxicity is increased in the patient with AKI or chronic kidney disease (CKD). Thus, the patient who is on diuretic therapy or has vomiting or diarrhea that results in true volume depletion is vulnerable to toxic drug effects on the kidney. ... Some strategies to prevent cisplatin nephrotoxicity include intravenous volume ... WebApr 12, 2024 · In cancer patients, physicians should try to set preventive strategies to safeguard the renal function, avoiding the concomitant use of nephrotoxic drugs, personalizing the dose of chemotherapy according to the glomerular filtration rate (GFR) and using an appropriate hydration therapy in combination with nephroprotective compounds.
WebIntroduction. Cisplatin and platinum-based chemotherapy (PBC) are broadly used potent antineoplastic treatments. The cytotoxic substance, cisplatin, was first discovered in Escherichia coli as an anti-infective agent, and its antitumor activity was reported several years later. 1,2 PBC is widely applied to treat oncologic diseases, such as lymphoma, …
WebOct 26, 2010 · Cisplatin was first shown to inhibit cell division in 1965 . By 1969, cisplatin … underground water valve boxWebOct 19, 2024 · The best way to prevent or delay diabetic nephropathy is by maintaining a … underground water temperature by depthWebPrevention and management of cisplatin nephrotoxicity ID: 184 v.3 Endorsed This … underground water tanks sunshine coastWebNov 1, 2024 · Even after a single-dose injection of cisplatin (50–100 mg/m 2), approximately one-third of the patients develop acute kidney injury (AKI) characterized by a rapid decline in renal function. Patients with AKI have a 50% mortality rate, and surviving AKI patients are likely to develop chronic kidney disease in months to years [2]. underground waterway fishing spot genshinWebApr 24, 2024 · The findings contained within this systematic review show that (a) hydration is essential for all patients to prevent cisplatin‐induced nephrotoxicity, (b) short‐duration, low‐volume, outpatient hydration regimens appear to be safe and feasible, even in patients receiving intermediate‐ to high‐dose cisplatin, (c) magnesium supplementation (8–16 … thoughtfully yoursWebProphylaxis and treatment Prevention and management of cisplatin nephrotoxicity ID: 184 v.3 Endorsed This document is an evidence based summary to complement treatment protocols and includes background and rationale for specific point of care actions. It is not intended to be a comprehensive literature review of all available evidence. On this page thoughtful magyarulWebMar 31, 2024 · The goal of this activity is to provide medical news to primary care clinicians and other healthcare professionals in order to enhance patient care. Upon completion of this activity, participants will be able to: Describe the mechanisms of nephrotoxic drugs. Review general preventive measure to avoid nephrotoxicity. Disclosures thoughtfully gifts hot sauce