Trimethyltin effect on rat

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August undefined, 2024

WebFor example, a particular behavior, such as activity in an open field, may be changed in a dose-related fashion by drugs that have a recognized clinical effect in psychiatric … WebAug 15, 2002 · In contrast, rates of respiration by liver mitochondria isolated from rats treated in vivo with trimethyltin chloride, following prior treatment with clofibrate, were …

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WebDOI: 10.1016/0041-008X(85)90288-1 Corpus ID: 12130995; The effects of triethyltin and trimethyltin in rats responding under a DRL schedule of reinforcement. … WebApr 11, 2024 · Then, we modified this engineered strain by replacing UGT109A1 with its mutant UGT109A1-K73A, overexpressing the cytochrome P450 reductase ATR2 from Arabidopsis thaliana and the key enzymes of UDP-glucose biosynthesis to increase the production of 3β,12β-Di-O-Glc-PPT, although these strategies did not show any positive … lakes area yoga brainerd

Trimethyltin Neurotoxicity in the Rat as an Analogous Model of ...

WebFor example, a particular behavior, such as activity in an open field, may be changed in a dose-related fashion by drugs that have a recognized clinical effect in psychiatric patients, but the rat behavior may not have any clear relationship to the human psychopathology. WebMay 15, 2012 · This study was carried out to assess the behavioral effects of the non-psychostimulant drug atomoxetine, in rats prenatally-exposed to the organic compound trimethyltin chloride (TMT) and in spontaneously hypertensive rat (SHR), two rodent models of Attention Deficit/Hyperactivity Disorder (ADHD). At birth, neonatal reflexes (righting, … WebRats were trained to respond under a schedule of reinforcement in which only those responses separated by a 10-to 14-sec period of no responding produced a feed pellet … lake sasaginnigak canada

Autophagy is Activated In Vivo during Trimethyltin-Induced …

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WebAug 15, 2002 · Data presented in Fig. 1 demonstrate the, expected, powerful in vitro inhibition of ADP-stimulated mitochondrial respiration by trimethyltin chloride, 20 μM … WebAfter a single gastric dose of 4.0 mg/kg trimethyltin chloride (2.4 mg tin/kg) to rats, the blood and brain concn of trimethyltin (expressed as tin) were 39 ug/ml and 1.3 ug/g, respectively, while ... after the 4th weekly dose of 4.0 mg/kg the corresponding concn were 120 ug/ml and 3.5 ug/g.In the marmoset treated with 3.0 mg/kg trimethyltin chloride (1.8 … jenis jenis konsorsiumWebJun 4, 2013 · After injection of trimethyltin (TMT, 8.0 mg/kg, i.p.), which is a potent toxicant that selectively kills cells in the central nervous system, rats were administered Gugijihwang-Tang (100 mg/kg, p.o.) daily for two weeks, followed by the Morris water maze tasks and [F-18]FDG micro PET neuroimaging. jenis jenis konflik pdf

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Trimethyltin effect on rat

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WebAug 30, 2016 · To evaluate the effect of TMT on cochlear function, the CAP was recorded with the facial nerve canal electrode ... Wonderlin W.F., Bercegeay M. The trimethyltin syndrome in rats. Neurobehav. Toxicol. Teratol. 1982; 4:127–133. [Google Scholar] Fechter L.D., Clerici W.J., Yao L., Hoeffding V. Rapid disruption of cochlear ... WebMay 22, 2024 · Trimethyltin was first described as a potent nephrotoxicant in two studies where this compound was orally administered in rats (28, 41). TMT induced rats to a renal failure and there was a time-course relationship between the effects on the kidney and various neurological manifestations ( 28 ).

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WebMar 12, 2013 · Here, we conducted studies to compare the acute toxicity induced by trimethyltin (TMT) and dimethyltin (DMT), and investigated the cumulative toxic effects of … WebDec 21, 2014 · Pathophysiology of depression is a controversial issue. The present study aimed at investigating the pathophysiology of depression in trimethyltin (TMT) …

WebGorini. "Effect of CDP-choline on age-dependent modifications of energy- and glutamate-linked enzyme activities in synaptic and non-synaptic mitochondria from rat cerebral cortex", Neurochemistry International, 2012 Crossref Koda, T.. "Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats", Nutrition ... WebLarge pyramidal neurons of the hippocampus of a rat treated with trimethyltin (TMT) (7.3 mg TMT/kg, po) and killed 7 days later to show severe neuronal ... dorsal root ganglia, olfactory cortex, retina, and inner ear. TMT is increasingly exploited as a model neurotoxicant in rats to study the impact of chemical-induced altered hippocampal ...

WebTrimethyltin hese anatomical and behavioral indings have made TMT- (TMT) is an organotoxic compound with potent neuro- intoxicated rats an attractive model for degenerative diseases toxicant efects which is regarded as being particularly such as AD, the most common cause of dementia [9, 10]. useful for studying the response to injury on … WebJun 30, 2015 · This research work was done to investigate acute toxicological effect of trimethyltin chloride on the cerebellum of wistar rat. Ten adult male wistar rats were used for the study.

WebSep 1, 1985 · Male Wistar (Porton) rats were dosed by gavage with trimethyltin chloride in arachis oil at doses of 3, 6 and 10 mg kg. Water consumption and urine production were …

WebJun 15, 1985 · Trimethyltin is a neurotoxicant which produces a distinct pattern of neuronal cell death following peripheral administration of a single dose (8 mg/kg, i.p.) in rats. The … jenis jenis konstitusiWebThe triorganotin compound trimethyltin (TMT) is a highly toxic molecule which has a great impact on human health. The aim of this study was to investigate the specific alteration … jenis jenis konsultanWebMay 9, 2015 · Trimethyltin (TMT), which has a variety of applications in industry and agricultural, is a neurotoxin that is known to affect the auditory system as well as central nervous system of humans and experimental animals. However, the mechanisms underlying TMT-induced auditory dysfunction are poorly understood. To gain insights into the … lakes area eyecare perham mnWebCitations & impact Similar Articles Funding Effects of trimethyltin on the immune system of rats. ... lakes around salem indianaWebJan 12, 2024 · This study aimed to investigate whether the Protaetia brevitarsis seulensis (PB)’ water extract (PBWE) ameliorates trimethyltin (TMT)-induced seizures and hippocampal neurodegeneration. To investigate the potential neuroprotective effect of the PBWE in vitro, a lactate dehydrogenase (LDH) assay was conducted in TMT-treated … jenis jenis konservasiWebJul 11, 2024 · 1. Introduction. Trimethyltin (TMT) intoxication is regarded as an appropriate model of chronic neuronal degeneration associated with cognitive impairment, and is … lakes at ben eoinWebNov 1, 2024 · The stimulatory effect of albumin on luteinizing hormone-stimulated Leydig cell steroid production depends on its fatty acid content and correlates with … jenis jenis konsumen